The Iowa State Cyclones upset the LSU Tigers on Friday night, and in doing so left all remaining NCAA Tournament brackets busted.

It’s unclear how many perfect brackets remained as tipoff neared, but it was unlikely to be many. The tournament has been defined by bracket-wrecking upsets early on, including No. 11 Notre Dame over No. 6 Alabama, No. 12 Richmond over No. 5 Iowa and, of course, No. 15 Saint Peter’s over No. 2 Kentucky.