The 11-1 Kansas City Chiefs play host to the 8-4 Los Angeles Chargers in a highly anticipated AFC West duel. Let’s get into my Chargers vs Chiefs touchdown scorer best bets for SNF.

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Chargers vs Chiefs anytime touchdown scorer pick: DeAndre Hopkins (+250)

Odds available at FanDuel Sportsbook.

DeAndre Hopkins had his best game as a member of the Chiefs on Black Friday against the Los Angeles Raiders. Other than his drop, Hopkins showcased why the Chiefs made the move to acquire him to become their #1 target on the outside. He recorded a season-high 90 yards and was targeted twice in the red zone. Since Week 8 — Hopkins’ first game as a member of the Chiefs — he leads the wide receiver room in target share and receptions by a wide margin. I expect Patrick Mahomes to continue to look Hopkins way on Sunday night — and at a price of +250, Hopkins to score is an easy choice to lock in.

Chargers vs Chiefs anytime touchdown scorer pick: Isiah Pacheco (+110)

Odds available at FanDuel Sportsbook at time of publishing.

In Isiah Pacheco’s first game back since Week 2, he played 37% of the snaps — failing to get going on the ground. The Chiefs went away from the run game overall with Kareem Hunt also struggling. Mahomes threw the ball a season-high 46 times, as the Raiders put pressure on the Chiefs — who came in as double-digit favorites.

The recipe for success for the Chiefs is to run Pacheco and Hunt much more than they did last Friday. With more than a week off from their last game, I expect Pacheco to be much more involved in what should be a positive game script for Kansas City.