Week 16 of the 2023 NFL season gets underway with a crunch NFC matchup on Thursday Night Football between the New Orleans Saints and Los Angeles Rams. Both teams are battling it out to make it to the postseason and each currently holds a 7-7 record. While New Orleans can make it into the playoffs through either winning the NFC South or a wild-card spot, the Rams are purely fighting to be the #6 or #7 seed. This should be a great, competitive matchup, and here at Pickswise, we’re here to deliver you our top betting picks for the game. In this TNF betting guide, we have our best bets, Prop Holliday’s prop picks and even a Same Game Parlay at +1104 odds! Let’s dive in. 

NFL TNF Saints vs Rams Picks

• New Orleans Saints vs Los Angeles Rams predictions — our experts are up +32.5 units this season!

Saints vs Rams best player prop bets

• Saints vs Rams best player prop bet — find out Prop Holliday’s best pick for TNF
• Saints vs Rams touchdown scorer best bets — we cashed a +600 TD scorer winner on TNF last week!

Saints vs Rams Same Game Parlay 

• Lock in our Saints vs Rams Same Game Parlay at HUGE +1104 odds!

NFL Week 16 Predictions

Want even more NFL picks? Don’t miss our NFL predictions for EVERY Week 16 matchup, including a select few below: