San Diego Padres at Pittsburgh Pirates odds, picks and predictions


The San Diego Padres (37-41) open a 6-game road trip on Tuesday with the 1st game of a 3-game series against the Pittsburgh Pirates (35-42). First pitch from PNC Park is at 7:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Pirates odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 4 of 6 meetings in 2022

The Padres lost the final 2 games of a 3-game series at home against the Washington Nationals including an 8-3 defeat in the series finale on Sunday. They have lost 5 out of their last 7 games.

The Pirates have lost 12 of their last 13 games. They snapped a 10-game losing streak beating the Miami Marlins on Friday but lost 3 of 4 games in the series including the last 2 games. They were shut out 2-0 on Sunday.

Padres at Pirates projected starters

RHP Yu Darvish vs. LHP Rich Hill

Darvish (5-6 4.84 ERA) makes his 15th start. He has a 1.23 WHIP 2.8 BB/9 and 9.6 K/9 in 80 innings.

  • Last start: Loss 6 IP 4 ER 7 H 2 BB 6 K in 4-2 road loss to San Francisco Giants last Wednesday
  • Is 1-2 with 7.71 ERA in last 3 starts

Hill (6-7 4.34 ERA) makes his 16th start. He has a 1.37 WHIP 3.4 BB/9 and 8.2 K/9 in 83 innings.

  • Last start: Loss 5 2/3 IP 5 R (3 ER) 4 H 2 BB 4 K in 8-3 home loss to Chicago Cubs last Wednesday
  • Is 2-4 with 5.05 ERA in last 6 starts

Padres at Pirates odds

Provided by BetMGM SportsbookUSA TODAY Sports Scores and Sports Betting Odds hub Lines last updated at 10:45 a.m. ET.

  • Moneyline (ML): Padres -190 (bet $190 to win $100) | Pirates +155 (bet $100 to win $155)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (-115) | Pirates +1.5 (-105)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

Padres at Pirates picks and predictions


Padres 6 Pirates 4


The Pirates only have 1 win in their last 13 games and only 3 in their last 18. They have not scored more than 4 runs in their last 11 games and have been shut out 4 times. The Padres have lost 5 of their last 7 but are 9-9 in their last 18. However betting the Padres on the moneyline isn’t worth the action having to wager nearly twice what you can win.


Run line/Against the spread

The Pirates have covered the spread only twice in the last 9 games and only 3 times in their last 15. Seven of their last 8 losses have been by 2 or more runs. Five of the Padres’ last 6 wins have been by at least 2 runs.

BET PADRES -1.5 (-115).


The Pirates have struggled on offense scoring only 15 runs in their last 9 games. But with both pitchers with ERAs over 5.00 over their last several starts there is bound to be some offense early. The Padres have had 3 of their last 4 games finish with totals over 9 runs.

BET OVER 9 (-105).

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