The San Diego Padres (35-38) and San Francisco Giants (41-32) meet Wednesday for the 3rd game of a 4-game NL West set. First pitch from Oracle Stadium is slated for 9:45 p.m. ET (MLB Network).

Season series: Tied 2-2

San Diego has dropped the 1st 2 games of this series and the Padres are just 2-4 over their last 6 games. They sit 4th in  the NL West 8 1/2 game out of 1st place.

The Giants head into Wednesday night looking for their 10th consecutive victory. San Francisco’s offense has banged out an .877 OPS over that span. The Giants have outscored opponents 76-29 over the 9 straight wins and have surged into 2nd place in the NL West 2 1/2 games behind the Arizona Diamondbacks.

Padres at Giants projected starters

RHP Yu Darvish vs. RHP Ryan Walker

Darvish (5-5 4.74 ERA) makes his 14th start of the season. He owns a 1.20 WHIP 2.8 BB/9 and 9.6 K/9 in 74 innings.

• Has yielded 10 R over his last 10 1/3 IP and owns a 6.75 ERA in his last 7 starts
• Has a 9.75 ERA over his last 5 starts against San Francisco

Walker (2-0 1.65 ERA) is tabbed for his 2nd start. He has a 1.16 WHIP 1.7 BB/9 and 8.3 K/9 in 16 1/3 IP across 12 games (1 start).

• The 27-year-old rookie has pitched 20 1/3 IP in Triple-A this season (0.89 ERA 0.85 WHIP)
• Likely to serve as an opener with LHP Sean Manaea (2-3 5.84 ERA 1.38 WHIP) logging bulk innings behind him

Padres at Giants odds

• Moneyline: Padres -124 (bet $124 to win $100) | Giants +106 (bet $100 to win $106)
• Run line (RL)/Against the spread (ATS): Padres -1.5 (+128) | Giants +1.5 (-154)
• Over/Under (O/U): 8 (O: -115 | U: -105)

Padres at Giants picks and predictions

Prediction

Padres 5 Giants 4

Moneyline

The Padres are 9-3 in the last 12 series meetings and are 6-2 in the last 8 games in San Francisco.

San Diego is 0-6 in extra innings and 5-12 in 1-run games. The Friars are deserving of a better record than where they stand. Also peg their schedule as being tougher than the Giants’ so far.

San Diego batters own a .968 OPS against Manaea and their platoon numbers favor at-bats against southpaws.

TAKE THE PADRES (-124).

Run line/Against the spread

The Over has a lean and that makes the Run line favorite worth looking into. But we should want more return here PASS.

Over/Under

The Friars average just 3.70 RPG at home but on the road that figure jumps to 4.72.

A stiff breeze blowing outward is in the forecast for Wednesday’s game. With the way the Giants are hitting and the way the Padres have pounded Manaea in the past the lean is toward the Over.

BACK THE OVER 8 (-115).