The Memphis Grizzlies and Los Angeles Lakers play Game 6 of their Western Conference 1st-round series Friday at Crypto.com Arena. Tip-off is scheduled for 10:30 p.m. ET (ESPN).

The Lakers lead the series 3-2 and are also 3-2 against the spread (ATS).

The Grizzlies covered the spread as 4.5-point home favorites Wednesday in a 116-99 Game 5 win vs. the Lakers as the Under (222) hit. G Ja Morant had 31 points and 10 rebounds as Memphis avoided elimination.

F LeBron James scored just 15 points on 5-of-17 shooting in Game 5. The 19-time All-Star told reporters after the loss, “I’ll be better in Game 6.”

The last time the Grizzlies won at Crypto.com Arena was a 127-119 victory January 9, 2022.

Grizzlies at Lakers odds

• Moneyline (ML): Grizzlies +170 (bet $100 to win $170) | Lakers -210 (bet $210 to win $100)
• Against the spread (ATS): Grizzlies +4.5 (-110) | Lakers -4.5 (-110)
• Over/Under (O/U): 220.5 (O: -110 | U: -110)

Grizzlies at Lakers key injuries

Grizzlies

• C Steven Adams (knee) out
• F Brandon Clarke (Achilles) out
• G Luke Kennard (shoulder) questionable

Lakers

• C Anthony Davis (foot) probable
• F LeBron James (foot) probable
• G Dennis Schröder (Achilles) probable

For most recent updates: Official NBA injury report.

Grizzlies at Lakers picks and predictions

Prediction

Lakers 110, Grizzlies 101

Moneyline

PASS.

The Lakers (-210) should win their 5th straight home game vs. the Grizzlies, but there is no need to pay the higher price on the moneyline when Los Angeles should win by margin. Bet the spread and/or total instead.

Against the spread

BET LAKERS -4.5 (-110).

The Lakers should bounce back after getting blown out in Game 5. Los Angeles is 4-0 ATS in its last 4 games after a loss by more than 10 points and has covered in 4 straight at home vs. Memphis.

The Grizzlies have struggled to string together good performances lately and are 0-6 ATS in their last 6 games after a win. Memphis should struggle to keep it close Friday as James and the Lakers bounce back and clinch the series.

Over/Under

BET UNDER 220.5 (-110).

The Under is 5-1 in Memphis’ last 6 games after covering in its previous contest and 10-3-1 in Los Angeles’ last 14 vs. teams with a winning percentage above .600.

These teams have played low-scoring games vs. each other lately, with the Under going 17-5-1 in the last 23 meetings, and Friday’s matchup should stay under the total once again.