The 2023 NFL regular season is officially in full swing, and we’ve got another great slate to look forward to on Sunday. Why not celebrate this exciting group of games by going for a big payday? That’s right; we’re back with another mega parlay, NFL edition.

We’re going big and bold, so let’s not waste any more time. But before we dive in, don’t forget to check out our NFL picks for the side and total on every NFL game and all the latest NFL odds.

Indianapolis Colts ML (+166)

Houston Texans ML (+108)

New York Jets ML (+260)

Parlay odds: +1891

Let’s break down each of the legs:

Indianapolis Colts ML (+166)

Give me Gardner Minshew to start our parlay! The last time Anthony Richardson was sidelined with an injury and Minshew filled in, the Colts won outright as 8-point underdogs on the road against Baltimore. And they’ve got a much easier matchup on Sunday against an overrated Jaguars team. These teams played each other in Week 1, and the Colts were leading entering the fourth quarter despite the fact that it was Richardson’s NFL debut.

Indy has won 3 of 4 games since then, with the only loss in that span coming to the Rams in overtime. The Colts are a lot better than most people realize, and Shane Steichen looks like a great head coach to me. Jacksonville is coming off back-to-back games in London, so they’ve got to be a bit exhausted after spending multiple weeks in Europe and then having to adjust in the run-up to this game.

Now is not the time to buy high on the Jags following their surprise win over Buffalo in a high-variance London game. Remember, just a few weeks ago the Jaguars were getting blown out 37-17 by rookie CJ Stroud and the Texans. Trevor Lawrence took 5 sacks last week, so look out for DeForest Buckner in this one, who scored a defensive touchdown the last time these teams played each other.

Houston Texans ML (+108)

Speaking of CJ Stroud and the Texans, I’m jumping at the opportunity to get them as a home ‘dog against a mediocre Saints team. I haven’t seen anything to be optimistic about out of New Orleans, whereas Stroud already looks like an above-average quarterback after just a handful of games. The Ohio State product is averaging 7.9 yards per attempt, and has still yet to throw an interception.

He has led the Texans to 30+ points in 2 of the team’s past 3 games, including against a Mike Tomlin Steelers defense. Last week they lost on a last-second field goal on the road against a pretty solid Falcons team, which I’m not holding against them too much.

New Orleans has scored more than 20 points only once this season, and that was against a lifeless Patriots team. Right before their game against New England, they got demolished 26-9 by the Bucs. And before that they lost to a Packers team that’s currently floundering.

You can also check out our favorite NFL teaser picks and Week 6 player prop bets

New York Jets ML (+260)

What better way to wrap up a mega parlay than with our biggest ‘dog? The Jets have already beaten the Bills and almost beaten the Chiefs with Zach Wilson this season, so I don’t see why they won’t be able to hang with the Eagles with Wilson under center. Philly has started off 5-0, but I haven’t been quite as impressed as everybody else.

Their 5 wins have come against the Patriots, Vikings, Buccaneers, Commanders and Rams. Not exactly a murderer’s row. The Bucs are the only one of those teams that isn’t under .500, and I don’t think anyone is getting too excited about a win over Tampa Bay. This is arguably the Eagles’ toughest test of the season, and it’s certainly the toughest defense Jalen Hurts will have faced.

New York has one of the best defenses in the league, and they’ve already made life miserable for both Josh Allen and Patrick Mahomes this season. And the Eagles are also going to be without both Jalen Carter and Darius Slay in this one, two of their best players on defense.

The Jets also feature in this week’s millionaire maker 14-team parlay!