Seattle Mariners at San Francisco Giants odds, picks and predictions


The San Francisco Giants (46-38) welcome the Seattle Mariners (40-42) to Oracle Park Monday. First pitch is set for 9:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Mariners at Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting of 2023.

The Mariners beat the Tampa Bay Rays 7-6 on Sunday and 8-3 on Saturday after dropping the series opener on Friday and are 5-5 over their last 10 games. Seattle is 16-22 on the road this season.

The Giants return home where they are 23-19 after going 2-4 on a 6-game road trip. San Francisco is coming off an 8-4 loss to the New York Mets Sunday and is 4-6 over its last 10 games stumbling a little following a season-long 10-game win streak from June 11-21.

Mariners at Giants projected starters

RHP Bryan Woo vs. RHP Logan Webb

Woo (1-1 4.37 ERA) makes his 6th start. He has a 1.24 WHIP 2.4 BB/9 and 12.7 K/9 through 22 2/3 IP.

  • Was Seattle’s 6th-round pick in the 2021 draft and made his first major-league appearance on June 3
  • The Mariners are 3-2 in his 5 starts
  • Last start: No-decision 5 IP 2 R (1 ER) 6 H 1 BB 7 K in a 7-4 loss vs. Washington Nationals Tuesday

Webb (7-7 3.43 ERA) makes his 18th start. He has a 1.12 WHIP 1.7 BB/9 and 8.6 K/9 through 110 1/3 IP.

  • 3rd-most innings pitched in all MLB and 1.7 BB/9 leads National League
  • The Giants are 8-9 in his 17 starts
  • Last start: Loss 5 IP 5 ER 8 H 0 BB 5 K in a 6-1 defeat at Toronto Blue Jays Wednesday

Mariners at Giants odds

Provided by BetMGM SportsbookUSA TODAY Sports Scores and Sports Betting Odds hub Lines last updated at 9:08 a.m. ET.

  • Moneyline (ML): Mariners +115 (bet $100 to win $115) | Giants -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Mariners +1.5 (-185) | Giants -1.5 (+150)
  • Over/Under (O/U): 7.5 (O: -105 | U: -115)

Mariners at Giants picks and predictions


Mariners 5 Giants 4



The Giants are just 11-15 as a home favorite the 4th-worst mark in the league and one of only 6 teams to have a sub-.500 win rate in that scenario. Seattle is 10-13 as a road underdog but just won 2 of 3 games against the Rays who have the best record in MLB.

Webb struggled in his last start and the Giants haven’t been great with him on the mound the opposite of the Mariners with Woo.

Run line/Against the spread


I don’t see much value here either way. I don’t think the Giants -1.5 (+150) come out on top by multiple runs and I prefer the plus-money moneyline value with the visitors instead of the expensive price tag to get insurance on Seattle +1.5 (-185).


The Mariners have gone Over the total in their last 4 games against an RHP and are 4-0 to the Over in their last 4 games after a victory. Seattle is 42-39-1 O/U this season and 5-1 O/U in its last 6 games.

The Giants cashed the Over in their last game against the Mets and have scored 4 or more runs in 2 of their last 3 outings. Put it all together and take the OVER 7.5 (-105).

For more sports betting picks and tips check out and BetFTW.

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