Arizona Wildcats at Colorado Buffaloes Game Prediction

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Game Info:

  • Teams: Arizona Wildcats (4-3) at Colorado Buffaloes (3-5)
  • Date: Saturday, November 1
  • Time: 7:00 PM EST
  • Venue: Folsom Field, Boulder, CO
  • Line: Arizona -3.5, Over/Under 53.5

The Matchup: A Big 12 Battle of Attrition

The Arizona Wildcats travel to Folsom Field for a critical late-season Big 12 matchup against the Colorado Buffaloes. Both teams enter this contest facing significant headwinds, with injuries defining the narrative for their respective seasons. Arizona (4-3) looks to secure a key road win to improve its bowl positioning, while Colorado (3-5) is in desperation mode, needing a victory to keep its postseason hopes alive.

The betting line reflects a game expected to be close, with Arizona installed as a narrow 3.5-point road favorite. This indicates that despite playing on the road, the Wildcats are considered the slightly better team, even as both squads navigate extensive injury reports.

Arizona Wildcats Analysis

The Wildcats come into Boulder as favorites, but they are far from full strength. Reports from earlier in October described Arizona’s injury list as “a mile long,” suggesting they have been battling depth issues for weeks. Despite these challenges, they have managed a winning record and are still seen by oddsmakers as the superior team in this contest.

While specific player statuses can change weekly, the ongoing injury situation means Arizona has had to rely on its depth. The good news from recent weeks is that key players like linebacker Riley Wilson and defensive lineman Tre Smith were not on the injury report for their Big 12 opener, but the team’s overall health remains a persistent concern. For Arizona to cover the spread, they will need their available playmakers to exploit a similarly banged-up Colorado squad.

Colorado Buffaloes Analysis

It has been a difficult stretch for the Buffaloes, who have seen their season hampered by a seemingly endless stream of injuries. Multiple reports throughout October have highlighted the grim reality in Boulder, with one outlet noting “no good news in Colorado’s injury report” week after week.

The defense has been particularly hard-hit. According to The Ralphie Report, the defensive injury list has been “nearly identical” for consecutive weeks, with key players like cornerback RJ Johnson listed as out. This has put immense pressure on a unit struggling for consistency. On the offensive side, there is a glimmer of hope as wide receiver S. Brown is listed as probable, but the overall health of the team is a major question mark. At 3-5, the Buffs will need to rally at home and play their most complete game of the season to pull off the upset.

Prediction & Pick

This game projects as a “battle of the wounded.” Both teams are limping into this matchup, and the winner may simply be the team that is healthier or has the better “next man up.”

Arizona’s status as a road favorite is telling. Even with their own significant injury concerns, they are perceived to have more talent and stability than a Colorado team that has been in a tailspin. The Buffaloes’ defensive injuries, particularly in the secondary, could open the door for the Arizona offense to make just enough plays to create separation.

The total of 53.5 points feels a bit high for two teams struggling with attrition. Injuries often lead to sloppy execution, stalled drives, and an overall lack of offensive rhythm. While both defenses are vulnerable, it’s more likely this turns into a grind-it-out affair than a high-scoring shootout.

The Pick: Arizona -3.5

Total: Under 53.5

Sources:
Cardinals Injury Report I Arizona Cardinals – AZCardinals.com
Arizona Cardinals Injury Status – ESPN
Arizona’s injury report is a mile long before their meeting with BYU …
ARIZONA INJURY PREVENTION PLAN
Arizona – INJURY UPDATE: Keyshawn Whitehorse is awake …
Arizona Injury Law Group
First Arizona injury report released ahead of Big 12 season-opener …
Arizona – INJURY UPDATE: Last night during our Teams Challenge …
Worker’s Report of Injury Form | Industrial Commission of Arizona
Kansas State vs Arizona injury report: Major Dylan Edwards update …

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