Breaking down the opening odds and attempting to predict how the lines will move for some of the biggest matchups on the Week 6 college football schedule.

Another weekend of college football is in the books. Week 5 provided several thrilling finishes. numerous upsets, and a few VERY close calls. Yeah, we’re looking at you, Georgia. 

The action only figures to get more intense from here as the College Football Playoff race heats up. As we close in on the halfway point of the season, even teams who are not in the CFP mix still have the motivation to reach six wins in order to make a bowl game.

When it comes to our list of college football games to watch in Week 6, the noon window on Saturday really stands out. Multiple ranked matchups and a major rivalry game at the Texas State Fair headline the action. Throw in massive games in both the Pac-12 and SEC scheduled for later in the day and it promises to be another entertaining weekend of football!

Here are previews and analyses for our top seven games to watch in Week 6 of the 2022 college football season (odds via DraftKings Sportsbook).

Arkansas vs. (23) Mississippi State

Date: Saturday, Oct. 8, noon ET
TV: SEC Network
Location: Davis-Wade Stadium, Starkville, MS
Odds: MSU -5 | O/U 62

Aside from the third quarter, Arkansas was thoroughly outclassed in last week’s home game against Alabama. The Razorbacks will look to snap their two-game losing skid when they head to Starkville to face a newly-ranked Mississippi State team.

After the Bulldogs throttled Texas A&M in Week 5, it was no surprise to see oddsmakers open them as 6-point favorites. While DraftKings sits a full point lower at the time of writing, one would have to believe that the line will shift in Mississippi State’s favor. Head coach Mike Leach’s experienced roster may not be flying under the radar much longer.