Six weeks into the 2019 college football season, 16 of the 130 Football Bowl Subdivision teams remain undefeated. That number will steadily be trimmed, though.
Based on the remaining games, seven are guaranteed to lose at least once. For example, the Big Ten and SEC both have four unbeatens, but future games (Wisconsin at Ohio State, Penn State at Minnesota, Florida vs. Georgia and LSU at Alabama) will eliminate four.
Throw in a few other marquee conference games and inevitable upsets, and several more will drop a contest in 2019.
We've pulled out the prognosticator hat and identified the matchup that will blemish the record for most of the 16 teams. Not everyone has a projected loss before the College Football Playoff, though.